ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,422, issued on Dec. 23, was assigned to Oncocine LLC (Lebanon, Ore.).
"Therapeutic mRNA vaccine for malignancies" was invented by Patrick Iversen (Grand Junction, Colo.), Nickolas Kipshidze (New York) and Nodar Kipshidze (New York).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein is a method for cancer immunotherapy by administering to a subject an mRNA vaccine designed to express the carbonyl terminal segment of human chorionic gonadotropin (hCG). Also described an improved adjuvant by co-administration of an antisense IL-10 molecule to shift the vaccine immune response to enhanced T-cell responses to hCG. Other embodiments relate to ...