ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,222, issued on Oct. 6, was assigned to OMNIOX INC. (San Carlos, Calif.).
"Polymeric forms of H-NOX proteins" was invented by Gregory Kapp (San Francisco), Laura Serwer (San Francisco), Natacha Le Moan (San Francisco) and Stephen P. L. Cary (San Mateo, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the ...