US Patent Issued to OHIO STATE INNOVATION FOUNDATION on Oct. 6 for "Engineered cells and uses thereof" (American, Chinese Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,751,929, issued on Oct. 6, was assigned to OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio).

"Engineered cells and uses thereof" was invented by Yizhou Dong (Dublin, Ohio), Xucheng Hou (Columbus, Ohio) and Xinfu Zhang (Dalian, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to antigen presenting cells and uses thereof for treating sepsis. In some aspects, disclosed herein is an antigen presenting cell, comprising: a lipid-based nanoparticle, comprising: a recombinant polynucleotide, comprising: a first nucleic acid encoding an antimicrobial peptide; a second nucleic acid encoding cathepsin B; and a third nucleic acid ...