US Patent Issued to OHIO STATE INNOVATION FOUNDATION on June 23 for "RNA nanoparticle for liver cancer treatment" (Ohio Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,674, issued on June 23, was assigned to OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio).

"RNA nanoparticle for liver cancer treatment" was invented by Peixuan Guo (Columbus, Ohio), Satheesh Ellipilli (Columbus, Ohio), Hongzhi Wang (Columbus, Ohio), Congcong Xu (Columbus, Ohio) and Xin Li (Columbus, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods for targeted treatment of liver cancers with Paclitaxel and miR-122. The disclosed composition comprises RNA nanostructure conjugated to a hepatocyte targeting ligand, paclitaxel, and miR-122 for use in intracellular drug delivery to liver cancer cells. The...