US Patent Issued to Ohio State Innovation Foundation on April 7 for "Methods and compositions for inhibition of STAT3" (Ohio, Florida Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,265, issued on April 7, was assigned to Ohio State Innovation Foundation (Columbus, Ohio).

"Methods and compositions for inhibition of STAT3" was invented by Yuhong Yang (Dublin, Ohio), Chenglong Li (Gainesville, Fla.) and Michael Racke (Powell, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "In one aspect, the disclosure relates to prodrug compositions of a STAT inhibitor compound. In some aspects, the STAT is STAT3. Disclosed are pharmaceutical compositions comprising the prodrug inhibitors of STAT. In various aspects, the prodrug inhibitors of STAT can be used in methods of treating an inflammatory disorder, including multiple sclerosis, or a...