ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,399, issued on Dec. 16, was assigned to OcuTerra Therapeutics Inc. (Boston).

"Fluorinated integrin antagonists" was invented by Ben C. Askew (Marshfield, Mass.), Richard W. Heidebrecht (Somerville, Mass.), Takeru Furuya (Cambridge, Mass.), Mark E. Duggan (Tequesta, Fla.) and D. Scott Edwards (Bedford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating macular degeneration, diabetic retinopathy ...