US Patent Issued to OCEAN UNIVERSITY OF CHINA on March 17 for "Macrolide brefeldin a ester derivatives and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,219, issued on March 17, was assigned to OCEAN UNIVERSITY OF CHINA (Qingdao, China).

"Macrolide brefeldin a ester derivatives and use thereof" was invented by Changlun Shao (Qingdao, China), Yaoyao Jiang (Qingdao, China), Ming Liu (Qingdao, China), Changyun Wang (Qingdao, China), Meiyan Wei (Qingdao, China) and Cuifang Wang (Qingdao, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The ester derivatives of brefeldin A represented by Formula (I) in the inhibition of tumor proliferation. The compounds are prominent in the prevention or treatment of hyperproliferative diseases, including liver cancer, leukemia, breast cancer, colon adenocarcinoma,...