ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,161, issued on July 7, was assigned to NOVO NORDISK A/S (Bagsvaerd, Denmark).
"STAT3 targeting oligonucleotides and uses thereof" was invented by Marc Abrams (Natick, Mass.), Henryk T. Dudek (Belmont, Mass.), Harini Sivagurunatha Krishnan (Lexington, Mass.) and Shanthi Ganesh (Shrewsbury, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The subject matter disclosed herein is directed to modulating STAT3 gene expression using siRNA compositions and methods directed to affecting key cell populations supporting the growth and metastasis of cancer to affect the beneficial treatment, remission or removal of the underlying tumor in a patient."
The pat...