US Patent Issued to NOVO NORDISK on Jan. 27 for "Compositions and methods for inhibiting GYS2 expression" (Massachusetts Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,730, issued on Jan. 27, was assigned to NOVO NORDISK A/S (Bagsvaerd, Denmark).

"Compositions and methods for inhibiting GYS2 expression" was invented by Bob D. Brown (Littleton, Mass.), Natalie Pursell (Westborough, Mass.), Henryk T. Dudek (Belmont, Mass.) and Cheng Lai (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to oligonucleotides, compositions and methods useful for reducing GYS2 expression, particularly in hepatocytes. Disclosed oligonucleotides for the reduction of GYS2 expression may be double-stranded or single-stranded, and may be modified for improved characteristics such as stronger resistance t...