ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,501, issued on July 21, was assigned to Northwestern University (Evanston, Ill.) and Ann and Robert H. Lurie Children's Hospital of Chicago (Chicago).

"Maskless 2D/3D artificial subtraction angiography" was invented by Donald R. Cantrell (Chicago), Sameer A. Ansari (Chicago) and Leon Cho (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "During catheter-based angiography, the bone and soft tissues degrade visualization of the vasculature, which is of primary interest in such medical imaging procedures. The present disclosure includes systems and methods utilizing a trained neural network to remove the bone and soft tissue densities from post-co...