ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,488, issued on Oct. 21, was assigned to NOF Corp. (Tokyo) and UNIVERSITA' DEGLI STUDI DI PADOVA (Padua, Italy).
"Conjugate of bio-related substance and block polymer, and block polymer derivative for obtaining said conjugate" was invented by Hiroki Yoshioka (Kawasaki, Japan), Midori Hirai (Kawasaki, Japan), Masaki Kamiya (Kawasaki, Japan) and Gianfranco Pasut (Padua, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a modified bio-related substance that shows further prolonged half-life in blood and further improved stability in the blood of living organisms. In particular, the invention provides a conjugate of a block poly...