ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,813, issued on Jan. 20, was assigned to NIPPON SHINYAKU Co. LTD. (Kyoto, Japan).

"Substituted imidazo[4,5-bpyridines as M3 receptor PAMs" was invented by Koya Oikawa (Muko, Japan), Takuto Yamanaka (Kyoto, Japan), Sho Hirai (Kyoto, Japan) and Kazuhiko Wakita (Muko, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The purpose of the present invention is to provide a compound having M3 PAM activity.Examples of the present invention include azabenzimidazole compounds represented by the following formula [1] and pharmaceutically acceptable salts thereof.The compounds of the present invention have M3 PAM activity. In addition, since the compounds of t...