ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,723,043, issued on Sept. 1, was assigned to NIPPON CHEMIPHAR Co. LTD. (Tokyo).
"Method for preparing morphinan derivative having diaryl ether skeleton using novel copper catalyst" was invented by Masaaki Hirose (Saitama, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method which is for preparing a morphinan derivative having a diaryl ether skeleton represented by general formula (III) (In the formula, R1 represents a hydrogen atom, etc., R2, R3, and R4 are the same or different and each represent a hydrogen atom, or an arbitrary substituent, etc., R5 represent a hydrogen atom, a hydroxy group, etc., R14 and R15 are the same or diffe...