US Patent Issued to NINGBO COMBIREG PHARMACEUTICAL TECHNOLOGY on March 17 for "Deuterated 1,4-benzodiazepine-2,5-dione compound and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,213, issued on March 17, was assigned to NINGBO COMBIREG PHARMACEUTICAL TECHNOLOGY Co. LTD. (Zhejiang, China).

"Deuterated 1,4-benzodiazepine-2,5-dione compound and use thereof" was invented by Gang Liu (Zhejiang, China), Yao Ma (Zhejiang, China) and Wenjun Yu (Zhejiang, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a deuterated 1,4-benzodiazepine-2,5-dione compound and the use thereof. Provided is a compound as represented by formula I or a pharmaceutically acceptable salt thereof. The disclosed 1,4-benzodiazepine-2,5-dione active compound maintains the activity of inhibiting tumor cells and tumor stem cells, and prolongs the ...