ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,282, issued on Sept. 15, was assigned to NIKKISO Co. LTD. (Tokyo).

"Blood purification apparatus" was invented by Kazuya Tsuji (Makinohara, Japan), Takuya Maeda (Makinohara, Japan) and Hikaru Chiaki (Makinohara, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "In draining liquid in an AV-coupling-type blood circuit, it is determined that the blood circuit is in an AV-coupled state. A blood purification apparatus can switch between an open state in which fluid can flow through a blood removal side circuit and a blood return side circuit and a closed state in which the fluid cannot flow therethrough. The apparatus generates a difference in pressu...