ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,746,111, issued on Sept. 29, was assigned to NIIOS-USA INC. (San Diego).

"Donor overlay for treatment or alleviation of anterior corneal disorders" was invented by Gerrit Reinold Jacob Melles (Rotterdam, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to methods for the treatment or alleviation of an anterior corneal disorder in a subject in need thereof comprising removing corneal epithelial cells from an eye of said subject without removing any corneal tissue or other ocular tissue located posterior to the corneal epithelial cell layer; and positioning an overlay comprising a Bowman layer (BL), Descemet membrane (DM) ...