ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,800, issued on June 2, was assigned to NICOX SA (Sophia Antipolis, France).

"Nitric oxide releasing phosphodiesterase type 5 inhibitor" was invented by Nicoletta Almirante (Milan), Stefania Brambilla (Merone, Italy), Laura Storoni (Cesano Maderno, Italy), Francesco Impagnatiello (Milan) and Elena Bastia (Milan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Nitric oxide releasing phosphodiesterase type 5 (PDE5) inhibitors of formula (I) or (Ib) or (II) or a stereoisomer or a pharmaceutically acceptable salt thereof: useful for the treatment of ocular condition associated with elevated intraocular pressure such as ocular hypertension, glaucoma or retin...