ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,433, issued on July 14, was assigned to New York Blood Center Inc. (Rye, N.Y.).
"Compounds for treatment of hemolysis-and inflammasome-associated diseases" was invented by Hui Zhong (New York) and Karina Yazdanbakhsh (New York).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of treating a complication of a hemolysis and/or an inflammasome activation-associated disease comprising administering to a patient in need thereof quinine, or a derivative or salt thereof, or the combination of quinine and hemin. Also disclosed is a method of reducing alloimmunization in chronically transfused subjects, comprising administering to a ...