ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,749, issued on June 9, was assigned to NEUSCO BIOTECH Ltd. (Shanghai).

"Preparation and application of tricyclic pyrimidinone compound and its composition" was invented by Zhenghua Gu (Shanghai), Dongqin Wang (Shanghai) and Youhong Hu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a tricyclic pyrimidinone compound of Formula (I) or a pharmaceutically acceptable salt thereof, which is a novel Lp-PLA2 inhibitor useful in treating neurodegeneration-related diseases such as Alzheimer's disease (AD), glaucoma and age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis."

The patent was filed on J...