US Patent Issued to Nephris on June 9 for "Methods for treating diabetic kidney disease and glomerular disease" (American, Italian Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,780, issued on June 9, was assigned to Nephris SrL (Milan).

"Methods for treating diabetic kidney disease and glomerular disease" was invented by Paolo Fiorina (Boston) and Francesca D'Addio (Milan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are provided for delaying onset or progression of kidney damage, or treating kidney disease, in a subject who has type 1 diabetes or type 2 diabetes or glomerular disease. The methods comprise administering to a subject with type 1 or type 2 diabetes or glomerular disease an effective amount of an agent capable of inhibiting NBL1 activity, and in particular, capable of inhibiting NBL1-mediated toxicity...