US Patent Issued to National University of Singapore on March 17 for "Isthmin 1 for treatment of lung inflammation" (Singaporean Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,132, issued on March 17, was assigned to National University of Singapore (Republic of, Singapore).

"Isthmin 1 for treatment of lung inflammation" was invented by Ruowen Ge (Singapore), Yin Weng Terence Lam (Singapore) and Wai-Shiu Fred Wong (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are polypeptides including an amino acid sequence having at least 70% sequence identity with an Isthmin 1 (ISM1) protein or a GRP78-activating fragment thereof, as well as expressible nucleic acids encoding said polypeptides. Uses of such agents, as well as methods for inducing apoptosis in alveolar macrophages and/or for treating, amelio...