ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,576, issued on March 3, was assigned to National University Corporation Kumamoto University (Kumamoto, Japan).
"Therapeutic agent for vascular disorder" was invented by Takumi Era (Kumamoto, Japan), Sayaka Watanabe (Tokyo) and Tomoe Kusayanagi (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "An object is to provide a drug that effectively treats a vascular disorder caused by excessive synthesis and secretion of a type IV collagen protein from a vascular endothelial cell. Provided are [1] a therapeutic agent for a vascular disorder associated with excessive synthesis and secretion of a type IV collagen protein; [2] a therapeutic agent for a dise...