ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,076, issued on Aug. 25, was assigned to NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (Kobe, Japan).
"Method for increasing mutation introduction efficiency in genome sequence modification technique, and molecular complex to be used therefor" was invented by Keiji Nishida (Kobe, Japan), Akihiko Kondo (Kobe, Japan), Takayuki Arazoe (Kobe, Japan) and Zenpei Shimatani (Kobe, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method of modifying a targeted site of a double-stranded DNA, comprising a step of introducing a complex wherein a nucleic acid sequence-recognizing module that specifically binds to a target nu...