US Patent Issued to NantBio on April 7 for "Anti-CTLA4 monoclonal antibodies and chimeric antigen receptors" (California Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,307, issued on April 7, was assigned to NantBio Inc. (Culver City, Calif.).

"Anti-CTLA4 monoclonal antibodies and chimeric antigen receptors" was invented by Clifford Anders Olson (Culver City, Calif.), Shiho Tanaka (Culver City, Calif.), Kayvan Niazi (Culver City, Calif.), Melanie Hermreck (Culver City, Calif.), Thomas H. King (Culver City, Calif.) and Zhimin Guo (Culver City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are presented in which selected polypeptide compounds bind to CTLA-4. Most typically, binding is mediated by selected VH and/or VL domains, and preferred compounds are prepared as scFv, IgG, or CAR...