US Patent Issued to NANJING CHEMPION BIOTECHNOLOGY on March 3 for "Tedizolid intermediate and efficient preparation method thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,482, issued on March 3, was assigned to NANJING CHEMPION BIOTECHNOLOGY Co. LTD. (Nanjing, China).

"Tedizolid intermediate and efficient preparation method thereof" was invented by Jian Chen (Nanjing, China), Zhiqiang Liu (Nanjing, China) and Rong Gu (Nanjing, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The efficient preparation method of a tedizolid intermediate includes the following steps: 1) subjecting 2-fluoro-4-substituted phenylacetic acid to a reaction with a Vilsmeier reagent, and adding a resulting reaction solution to an MX aqueous solution for quenching to obtain an intermediate shown in formula (II); and 2) subjecting the interm...