US Patent Issued to Myriad Women's Health on March 24 for "Copy number variant caller" (California Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,586,663, issued on March 24, was assigned to Myriad Women's Health Inc. (South San Francisco, Calif.).

"Copy number variant caller" was invented by Kevin R. Haas (Berkeley, Calif.), Xin Wang (San Francisco) and Peter V. Grauman (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Direct targeted sequencing (DTS) methods and a hidden Markov model (HMV) can be used to call the copy number of a segment of interest within a region of interest. Described herein are methods for calling a copy number variant or a copy number variant abnormality using an HMM, and methods for determining a copy number based on a copy number likelihood model, in a test ...