US Patent Issued to MUSC Foundation for Research Development, New York University, The United States Government as Represented by the Department of Veterans Affairs on March 3 for "Compositions and methods targeting the nucleotide free state of RAS to block oncogenic signaling and transformation" (New York, South Carolina Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,537, issued on March 3, was assigned to MUSC Foundation for Research Development (Charleston, S.C.), New York University (New York) and The United States Government as Represented by the Department of Veterans Affairs (Washington).

"Compositions and methods targeting the nucleotide free state of RAS to block oncogenic signaling and transformation" was invented by John O'Bryan (Charleston, S.C.), Shohei Koide (New York) and Akiko Koide (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides compositions and methods for binding Ras in a nucleotide free state (apo RAS) and inhibiting Ras signaling. In one embodiment, the inventi...