ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,172, issued on March 31, was assigned to MORPHOSYS GMBH (Planegg, Germany).
"Complex-specific antibodies and antibody fragments and its use" was invented by Stefan Haertle (Mammendorf, Germany), Christian Frisch (Munich) and Achim Knappik (Moorenweis, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antibodies and fragments thereof that specifically detect the complex of a specific cognate antigen-binding moiety, in particular antibodies, and its antigen. The antibodies of the present disclosure do not bind either said cognate antigen binding moiety or said antigen alone and this can be used e.g. to directly det...