ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,047, issued on Jan. 20, was assigned to ModernaTX Inc. (Cambridge, Mass.).
"mRNA quantification methods" was invented by John Joyal (Cambridge, Mass.), Penggao Duan (Cambridge, Mass.), Kristian Link (Cambridge, Mass.), Nicholas J. Amato (Cambridge, Mass.) and Huijuan Li (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for determining a concentration of RNA (e.g. mRNA) in a solution. Certain aspects of the disclosure relate to digesting the target RNA polymer by adding a base to a solution of RNA, optionally comprising at least one chemically modified nucleotide, and incubating the mixture to digest the RNA...