ALEXANDRIA, Va., March 17 -- United States Patent no. 12,578,331, issued on March 17, was assigned to Mobius Biotechnology GmbH (Vienna).
"Monolayer of PBMCs or bone-marrow cells and uses thereof" was invented by Giulio Superti-Furga (Vienna), Berend Snijder (Vienna) and Gregory Vladimer (Vienna).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to peripheral blood mononuclear cell (PBMC) monolayers or bone-marrow cell monolayers and methods for its culture and corresponding uses of said monolayers. The present invention also relates, in some aspects, to screening methods comprising the PBMC monolayer or bone-marrow cell monolayer of the invention for determination of response or lack of re...