ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,079, issued on March 17, was assigned to MIRUM PHARMACEUTICALS INC..

"Methods for treating cholestasis" was invented by Thomas Jaecklin (Delemont, Switzerland) and Alejandro Dorenbaum (Mill Valley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for treating cholestasis in a subject having a liver disease. The method includes administering to the subject an Apical Sodium-dependent Bile Acid Transporter (ASBTI). More specifically, the present invention relates to methods for treating cholestasis in a subject where the method includes administering an ASBTI to a subject at a dose of at least 10 Mug/kg/day."

The pate...