ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,940, issued on June 9, was assigned to MICROSOFT TECHNOLOGY LICENSING LLC (Redmond, Wash.).
"Enzymatic oligonucleotide assembly using hairpins and enzymatic cleavage" was invented by Yuan-Jyue Chen (Seattle), Bichlien Hoang Nguyen (Seattle) and Karin Strauss (Seatte, Wash.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Sequential assembly of oligonucleotide hairpins is used to create oligonucleotides with specific sequences. Each oligonucleotide hairpin includes a payload region containing one or more nucleotides that are added to the end of an anchor strand. Overhang regions on the oligonucleotide hairpins hybridize to anchor strands attached to a s...