ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,772, issued on Aug. 18, was assigned to MICROSOFT TECHNOLOGY LICENSING LLC (Redmond, Wash.).
"Non-amplifiable polynucleotides for encoding information" was invented by Bichlien Hoang Nguyen (Seattle), Yuan-Jyue Chen (Seattle) and Jake Allen Smith (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Polynucleotides used for encoding information are synthesized with universal base analogs that participate in pi-stacking interactions but do not form Watson-Crick hydrogen bonds with other bases. The universal base analogs may have pyrrole-based bases such as 5-nitroindole (5NI). Inclusion of the universal base analogs in the polynucleotides prevents ...