ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,411, issued on May 26, was assigned to MGGM LLC (Kerhonkson, N.Y.) and University of Padova (Padua, Italy).

"Structurally modified opioids for prevention and treatment of diseases and conditions" was invented by Paolo L. Manfredi (Miami Beach, Fla.), Charles E. Inturrisi (New York), Andrea Mattarei (Perarolo di Vigonza, Italy), Sara De Martin (Vigonza, Italy), Jacopo Sgrignani (Almenno San Salvatore, Italy) and Andrea Cavalli (Zurich).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the present invention are directed to structurally modified opioids (SMOs) that result in improved modulating activity at the NMDAR and improved PK and PD paramet...