ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,405, issued on Sept. 9, was assigned to Mesoblast International Sarl (Meyrin, Switzerland).
"Enhanced MSC preparations" was invented by Samson Tom (Basking Ridge, N.J.), Christopher Ton (Lansdale, Pa.) and Alla Danilkovitch (Columbia, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides preparations of MSCs with important therapeutic potential. The MSC cells are non-primary cells with an antigen profile comprising less than about 1.25% CD45+ cells (or less than about 0.75% CD45+), at least about 95% CD105+ cells, and at least about 95% CD166+ cells. Optionally, MSCs of the present preparations are isogenic and can be ex...