US Patent Issued to Merck Sharp & Dohme on May 19 for "Spirocyclic-substituted 6,7-dihydro-pyrano[2,3- dpyrimidine inhibitors of KRAS G12C mutant" (Massachusetts Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,559, issued on May 19, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Spirocyclic-substituted 6,7-dihydro-pyrano[2,3- dpyrimidine inhibitors of KRAS G12C mutant" was invented by Yongxin Han (Needham, Mass.), Elisabeth Hennessy (Weston, Mass.), Andrew J. Hoover (Framingham, Mass.), Jesus Moreno (Dorchester Center, Mass.), David L. Sloman (Newton, Mass.), Uma Swaminathan (Auburndale, Mass.) and Yingchun Ye (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides compounds of Formula (I)or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, CS, R2, and R3 are as described herein. The compounds or the...