ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,258, issued on Sept. 15, was assigned to Memorial Sloan Kettering Cancer Center (New York).
"Radioligands for pretargeted PET imaging and methods of their therapeutic use" was invented by Brian Zeglis (New York), Jason Lewis (New York), Thomas Reiner (New York), Jacob Lee Houghton (New York), Jan-Philip Meyer (New York) and Christian Brand (New York).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are Tz/TCO-based pretargeting strategies using an Al[18F]-NOTA-labeled tetrazine radioligand. This imaging strategy enables delineation of cancer at earlier time points compared to other imaging strategies and further decreases the radiatio...