US Patent Issued to MEMORIAL SLOAN-KETTERING CANCER CENTER on July 14 for "Modulating permeability of the blood cerebrospinal fluid barrier" (New York Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,501, issued on July 14, was assigned to MEMORIAL SLOAN-KETTERING CANCER CENTER (New York).

"Modulating permeability of the blood cerebrospinal fluid barrier" was invented by Adrienne Boire (New York) and Joan Massague (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods and compositions for modulating the blood CSF barrier and for diagnosing, preventing and/or treating leptomeningeal metastasis. In particular embodiments of the invention, the permeability of the blood CSF barrier is modulated by agonists or antagonists of Complement Component 3 (C3) or its receptor."

The patent was filed on Feb. 8, 2022,...