US Patent Issued to MeiraGTx Gene Regulation, University of Heidelberg on Oct. 27 for "Modified AAV capsid proteins for treatment of arthritic disease" (Dutch, German, American Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,474, issued on Oct. 27, was assigned to MeiraGTx Gene Regulation Ltd. (London) and University of Heidelberg (Heidelberg, Germany).

"Modified AAV capsid proteins for treatment of arthritic disease" was invented by Sabine Maria Gertrude Van Der Sanden (Amsterdam), Susanne Anna Snoek (Heiloo, Netherlands), Niels Broekstra (Nieuwkoop, Netherlands), Jonathan Douglas Finn (Melrose, Mass.), Dirk Grimm (Heidelberg, Germany) and Kathleen Borner (Schriesheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to recombinant adeno-associated virus (rAAV) virions for gene therapy, wherein the rAAV virions comprise a novel capsid protei...