US Patent Issued to MEIOGENIX, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE on June 23 for "Use of a deficient fusion protein for nuclease activity so as to induce meiotic recombinations" (French Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,663, issued on June 23, was assigned to MEIOGENIX (Paris), INSTITUT CURIE (Paris Cedex, France), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris) and SORBONNE UNIVERSITE (Paris).

"Use of a deficient fusion protein for nuclease activity so as to induce meiotic recombinations" was invented by Alexandre Serero (Colombes, France) and Alain Nicolas (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a fusion protein comprising a domain of a nuclease from the class II CRISPR system, and a Spoll domain, wherein both domains of the fusion protein have deficient nuclease activity, as well as the use of this protein to i...