ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,349, issued on Jan. 27, was assigned to Medtronic Inc. (Minneapolis).

"Drug formulations for reservoir-based delivery" was invented by Chandrasekhar R. Rajagopalan (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for formulating a drug for use with a medical device, such as a reservoir-based delivery device, includes (i) determining that an ingredient of a drug formulation has a differential Hansen Solubility Parameter (HSP) value for a component of a medical device of less than 10; (ii) identifying a range of pH at which the ingredient has a high solubility in an aqueous solution; and (iii) preparing an aqueous drug formulation ...