US Patent Issued to Maze Therapeutics on Jan. 27 for "Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof" (California Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,453, issued on Jan. 27, was assigned to Maze Therapeutics Inc. (South San Francisco, Calif.).

"Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof" was invented by David John Morgans Jr. (Los Altos, Calif.), Kevin Mellem (Redwood City, Calif.), Hannah L. Powers (San Diego), Patrick Sang Tae Lee (Walnut Creek, Calif.), Walter Won (San Diego) and Christopher Joseph Sinz (Walnut Creek, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds of formula (I'):or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein Y2, Y3, L1, L2, X1, X2, X3, X4, X5, Q1, R1, R...