US Patent Issued to Massachusetts Institute of Technology on Oct. 21 for "Activatable therapeutic peptides and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,418, issued on Oct. 21, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Activatable therapeutic peptides and uses thereof" was invented by Sangeeta N. Bhatia (Cambridge, Mass.) and Chayanon Ngambenjawong (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are fusion protein, comprising (a) at least one X1 domain comprising a half-life extension compound, including but not limited to a half-life extension polypeptide; (b) at least one X2 domain comprising an anionic block; (c) at least one X3 domain comprising a linker susceptible to cleavage at a site of disease, including but not limited to a...