US Patent Issued to Massachusetts Institute of Technology on Nov. 25 for "RNA cleavage-induced transcript stabilizer and uses thereof" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,119, issued on Nov. 25, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"RNA cleavage-induced transcript stabilizer and uses thereof" was invented by Ron Weiss (Newton, Mass.) and Breanna E. DiAndreth (Newbury Park, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are genetic circuits and encoded RNA transcripts that produce an output molecule in response to an RNA cleavage event that removes a degradation signal. In some embodiments, the genetic circuits described herein may be used for detecting RNA cleaver activities (e.g., in a cell). Methods of using the genetic circuits described herein in diagnos...