US Patent Issued to Massachusetts Eye and Ear Infirmary on July 28 for "Topotecan for proliferative vitreoretinopathy" (Massachusetts Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,110, issued on July 28, was assigned to Massachusetts Eye and Ear Infirmary (Boston).

"Topotecan for proliferative vitreoretinopathy" was invented by Leo A. Kim (Brookline, Mass.), Joseph F. Arboleda-Velasquez (Newton, Mass.), Dean Eliott (Boston) and Elizabeth Jeffries Rossin (Charlestown, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The use of topotecan, e.g., repeated dosing or sustained-release formulations of topotecan, for treating or reducing risk of proliferative vitreoretinopathy (PVR) or epiretinal membranes (ERM), e.g., after surgical vitrectomy to treat retinal detachment, is described herein."

The patent was filed on March 30, ...