US Patent Issued to MacroGenics on Jan. 27 for "PD-1-binding molecules and methods of use thereof" (Maryland, California Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,531, issued on Jan. 27, was assigned to MacroGenics Inc. (Rockville, Md.).

"PD-1-binding molecules and methods of use thereof" was invented by Kalpana Shah (Boyds, Md.), Douglas H. Smith (San Mateo, Calif.), Ross La Motte-Mohs (Boyds, Md.), Leslie S. Johnson (Darnestown, Md.), Paul A. Moore (North Potomac, Md.), Ezio Bonvini (Potomac, Md.) and Scott Koenig (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to selected anti-PD-1 antibodies capable of binding to both cynomolgus monkey PD-1 and to human PD-1: PD-1 mAb 1, PD-1 mAb 2, PD-1 mAb 3, PD-1 mAb 4, PD-1 mAb 5, PD-1 mAb 6, PD-1 mAb 7, PD-1 mAb 8, PD-...