US Patent Issued to LONZA on Dec. 16 for "Methods for improving production of biological products by reducing the level of endogenous protein" (Swiss Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,624, issued on Dec. 16, was assigned to LONZA LTD (Visp, Switzerland).

"Methods for improving production of biological products by reducing the level of endogenous protein" was invented by Robert Young (Visp, Switzerland), Peter Michael O'Callaghan (Visp, Switzerland), David James (Visp, Switzerland) and Stephen Jaffe (Visp, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure features methods, cells or cell lines, and compositions for increasing the amount of products, e.g., proteins, produced by a cell or cell line by reducing the level of a non-essential endogenous protein."

The patent was filed on July 12, 2019, und...