ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,385, issued on Aug. 26, was assigned to Life Edit Therapeutics Inc. (Durham, N.C.).

"RNA-guided nucleases and active fragments and variants thereof and methods of use" was invented by Gunjan H. Arya (Cary, N.C.), Michael Coyle (Chapel Hill, N.C.), Alexandra Briner Crawley (Cary, N.C.), Tedd D. Elich (Durham, N.C.) and Joel S. Parker (Apex, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, visualization of a target sequence of interest, and modifying the expression of a sequence of int...