US Patent Issued to LEADINGTAC PHARMACEUTICAL (SHAOXING) on May 12 for "Indazole derivative, and preparation method therefor and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,019, issued on May 12, was assigned to LEADINGTAC PHARMACEUTICAL (SHAOXING) Co. LTD. (Zhejiang, China).

"Indazole derivative, and preparation method therefor and use thereof" was invented by Yan Feng (Shanghai) and Shiqiang Li (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "A class of indazole derivatives targeting an IRAK4 kinase protein for degradation, and a preparation method therefor and the use thereof are provided. In particular, the compound of formula I, a preparation method therefor, and a pharmaceutical composition thereof and the use thereof are presented. The compound can significantly degrade the IRAK4 kinase protein in cells a...