ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,405,253, issued on Sept. 2, was assigned to Laboratory Corporation of America Holdings (Burlington, N.C.).
"Methods and systems for hydrophilic-phase extraction" was invented by Robert MacNeill (Monroe Township, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are embodiments of methods for oligonucleotide analysis using a novel solid-phase extraction and hydrophilic-interaction liquid chromatography. The unique polar-based retention methods provided herein provide a high-recovery extraction. The methods improve assay reliability and reproducibility and reach picomolar sensitivity with the demonstrably beneficial accurate mass platfo...